1 - Episode 1

Rash returns to the ED and is immediately thrown into dealing with an attack at a market in Holby, while Ethan attends the scene. And David’s son Ollie arrives at the ED out of the blue.

2 - Episode 2

Rash helps a patient through a terrible loss, Ethan is brought a case by a friend from the past, and Duffy struggles with being left home alone while Charlie is at work.

3 - Episode 3

An accident brings David and Ollie closer together, and Duffy learns how overlooked some care home residents can be.

4 - Episode 4

Archie takes justice into her own hands to support a wronged patient, a friend from Iain’s past helps him think about his future, and Rash struggles to cope as pressure mounts.

5 - Episode 5

Rash’s career is threatened when he is blamed for Mason’s mistake. Iain’s confidence is knocked by Jan and Ruby’s surprised reaction when they hear he’ll be going for the HEMS job. Effie gets onto the CF trial thanks to Ethan’s lies.

6 - Episode 6

David and Ollie continue to butt heads, Rash decides to fight to stay in Holby, and a new member joins the paramedic team.

7 - Episode 7

Mason struggles to ask for help in his most difficult week as a junior doctor, David’s bubble is burst when Rosalene starts to fight for custody, and Ethan struggles to convince Effie to go through with the trial.

8 - Episode 8

Ethan struggles to keep his personal life from distracting him at work, while Duffy fights to reclaim her confidence despite some devastating news.

9 - Episode 9

Rash and Mason finally make peace, and Archie is reunited with guilt when the abusive ex-teacher she had taken vengeance on returns to the ED.

10 - Episode 10

Tension rises between Ethan and Rash, while Rosa opens up to David about her past.

11 - Episode 11

Ethan regrets his actions when Effie's trial goes wrong, Jade faces a dilemma, and Danny’s impromptu visit to his childhood home isn't quite the family reunion he hoped for.

12 - Episode 12

During a routine CQC investigation, Robyn is devastated to realise she can’t rely on Duffy. Ethan stifles his feelings and turns his back on Effie, and Rash protects Mason from Dylan.

13 - Episode 13

Ruby tells Jan that she no longer wants to work with Lev after she learns about his shady past. Rosa and David put their fake relationship into action, and the terror attack continues to haunt Ethan.

14 - Episode 14

Rash can’t stand it when Mason saves the day, Charlie is shocked to learn that Duffy can’t look after herself, and Rosa realises her mum has lied to David.

15 - Episode 15

16 - Episode 16

17 - Episode 17

It's an emotional rollercoaster of a day for Rash as events take their toll on staff and patients alike. Dylan struggles in his role as clinical lead, and Archie is desperate to impress Dylan but instead accepts friendship from Will.

18 - Episode 18

19 - Episode 19

Jacob attempts to make a difference in two patients' lives, while Ruby helps Archie get to the bottom of an ED mystery.

20 - Episode 20

A desperate Charlie seeks help from an old foe, whilst Faith and Lev find themselves living through their worst nightmare.

21 - Episode 21

Marty suffers a betrayal, a guilt-ridden Charlie questions his decision to put Duffy in a care home, and Archie and Connie bond over their work.

22 - Episode 22

An anxious Charlie searches for Duffy, who is missing in hostile weather conditions. Meanwhile, Lev is unable to accept the severity of Luka's prognosis.

23 - Episode 23

The ED pulls together in Charlie’s time of need, and Connie struggles to conceal her guilt from Archie.

24 - Episode 24

Ruby and Violette's relationship is pushed to the limit and Harmony's life is put in danger. Will struggles to finish a tedious report for Connie and turns to Lara for help, but he soon learns he should not mix his personal life with his work. Elsewhere, tensions run high when Ethan and Rash are forced to work

25 - Episode 25

Violette tries to get clean in rehab and prepares to fight Ruby for custody of baby Harmony. Faith struggles to cope with Luka’s diagnosis and considers joining a support group.

26 - Episode 26

Faith and Lev prepare for Luka’s surgery. Charlie returns to work earlier than expected, throwing himself into work as a distraction from his grief, but soon becomes agitated when he realises a few things in the ED have changed in his absence.

27 - Episode 27

Ruby fails to juggle Harmony and work, and Marty pushes Jade to the limit.

28 - Episode 28

New paramedic Fenisha makes a big impact, and Jacob is forced to go behind Charlie’s back.

29 - Episode 29

A heartbroken Lev struggles with Luka’s chemotherapy, and grieving Charlie finally snaps.

30 - Episode 30

Marty finally acknowledges how dangerous his behaviour has been outside of work and decides to change his ways. Meanwhile, Ethan questions what he really wants when Fenisha turns him down, and David suggests that Dylan's behaviour indicates feelings towards Faith, but Dylan denies it. Starring Shaheen Jafargholi and George Rainsford.

31 - Episode 31

Rash defies Connie while dealing with a complex case, and Ruby makes a life-changing decision.

32 - Episode 32

Fenisha's happiness comes crashing down, and a familiar face is brought into the ED.

33 - Episode 33

Noel’s suspicions are proved right when he catches a predator, and Fenisha battles with a difficult decision.

34 - Episode 34

Fenisha pushes Jan too far, Jade must confront her past, and Jacob makes an unexpected friend.

35 - Episode 35

When Charlie inadvertently gets caught up in a hostage situation at the ED, he must decide where his loyalties lie. Dylan does everything he can to keep Faith safe, putting his life on the line in the process. Will asks Fenisha for a second chance.

36 - Episode 36

Jade meets her birth mother and finally uncovers the truth behind her past, whilst Charlie is reminded of Duffy when treating a man who has recently received a heart transplant.

37 - Episode 37

Lev reflects on a traumatic childhood after connecting with a patient of similar heritage, and Jan struggles to prioritise her marriage over her work.

38 - Episode 38

Ethan battles his PTSD and throws himself into action after a dangerous incident at Holby Comic Con, and Faith leans on Dylan for support after Luka's latest scan.

39 - Episode 39

Jacob is concerned when Nate is brought into the ED struggling to breathe, and temptation gets the better of Lev.

40 - Episode 40

David struggles to manage his bipolar symptoms as his past comes back to haunt him, and Dylan’s morals are pushed to their limit.

41 - Episode 41

An utterly conflicted Dylan struggles to contain his fury at Lev, and Fenisha steps up to help in Jan’s hour of need.

42 - Episode 42

Jacob betrays Connie’s trust, Noel makes a heartbreaking mistake, and opinions in the ED are divided when an illegal stowaway falls from the sky.

43 - Code Orange

Marty reconnects with his homophobic father, and Rash is forced to intervene as disaster strikes the ED and the team are thrown into chaos.