Nurse Hayley Roberts joins SkyMed, a team of young medics and pilots flying air ambulances across Northern Manitoba. As they navigate life-saving missions, they also confront personal challenges, forging deep bonds amidst the isolation.

SkyMed expands its operations, introducing new territories and team members. The crew faces intensified emergencies and evolving relationships, testing their resilience and unity.

In the aftermath of a team member’s loss, SkyMed faces internal upheavals and external challenges. New leadership and personal trials push the crew to redefine their mission and relationships.