Isaac - Season 1
1 - Mandy Moore
Air Date: November 25, 2005
2 - Keira Knightley
Air Date: December 5, 2005
3 - Elle MacPherson
Air Date: December 6, 2005
4 - Wynonna Judd
Air Date: December 8, 2005
5 - Amanda Bynes
Air Date: December 9, 2005
6 - Lee Ann Womack
Air Date: December 12, 2005
7 - The Sopranos' Steve Schirripa
Air Date: December 13, 2005
8 - Jon Favreau
Air Date: December 14, 2005
9 - Rob and Amber from Survivor
Air Date: December 15, 2005
10 - Carla Gugino & Elisabeth Hasselbeck
Air Date: December 16, 2005
11 - Tom Arnold
Air Date: December 19, 2005
12 - Shania Twain
Air Date: December 20, 2005
13 - Niecy Nash
Air Date: December 21, 2005
14 - Andie MacDowell
Air Date: December 22, 2005
15 - Sarah Jessica Parker
Air Date: December 23, 2005
16 - Rachael Ray
Air Date: December 26, 2005
17 - Selma Blair
Air Date: December 27, 2005
18 - Matthew Modine
Air Date: December 28, 2005
19 - Rent's Anthony Rapp
Air Date: December 29, 2005
20 - Gastineau Girls
Air Date: December 30, 2005
21 - Isaac Makes You Fashion Fabulous
Air Date: January 1, 2006
22 - Madonna
Air Date: January 2, 2006
23 - Finola Hughes
Air Date: January 3, 2006
24 - Isaac and the City
Air Date: January 8, 2006
25 - Sela Ward
Air Date: January 9, 2006
Sela Ward; Jaime Pressly. Also: a segment on ice-cream recipes.
26 - Andrew Firestone
Air Date: January 13, 2006
27 - Rob Morrow
Air Date: January 18, 2006
28 - Cynthia Nixon
Air Date: January 20, 2006
29 - Nia Long
Air Date: January 23, 2006
30 - Bo Bice & Shannon Elizabeth
Air Date: January 27, 2006
31 - Margaret Cho
Air Date: January 30, 2006
32 - Michael Moloney
Air Date: February 3, 2006
33 - Kimora Lee Simmons
Air Date: February 10, 2006
34 - Isaac's Glamour Girls
Air Date: February 11, 2006
35 - Iman
Air Date: February 13, 2006
36 - Isaac Strikes Again
Air Date: February 19, 2006
37 - Rosie Perez
Air Date: February 21, 2006
38 - Lisa Loeb
Air Date: February 24, 2006
39 - S. Epatha Merkerson & J.C. Chasez
Air Date: February 27, 2006
40 - Gabrielle Union
Air Date: March 3, 2006
41 - Isaac's It Girls
Air Date: March 4, 2006
42 - Jamie Lynn Sigler
Air Date: March 6, 2006
43 - Gina Gershon
Air Date: March 10, 2006
44 - Huey Lewis
Air Date: March 13, 2006
45 - Tony Danza
Air Date: March 16, 2006
46 - Isaac's Famous Friends
Air Date: March 18, 2006
47 - Isaac's TV Darlings
Air Date: April 6, 2006
48 - Isaac's Celebrity Field Trips
Air Date: April 14, 2006
49 - Keira Knightley
Air Date: May 12, 2006
50 - Selma Blair
Air Date: May 13, 2006
51 - Niecy Nash
Air Date: May 14, 2006
52 - Finola Hughes
Air Date: May 15, 2006
53 - Madonna
Air Date: May 16, 2006
54 - Gastineau Girls
Air Date: May 19, 2006
55 - Lisa Loeb
Air Date: May 22, 2006
56 - Jamie Lynn Sigler
Air Date: May 25, 2006