Best Time Ever with Neil Patrick Harris - Season 1

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Reese Witherspoon

1 - Reese Witherspoon

Air Date: September 15, 2015

Reese Witherspoon serves as the celebrity guest announcer during the series premiere of this variety show hosted by Neil Patrick Harris, which features A-list stars, performances, stunts, comedy skits, mini game shows, audience giveaways and hidden camera pranks. Based on the British series "Ant & Dec's Saturday Night Takeaway."

Alec Baldwin

2 - Alec Baldwin

Air Date: September 22, 2015

Emmy Award winner Alec Baldwin serves as this week's celebrity guest announcer.

Tyler Perry

3 - Tyler Perry

Air Date: September 29, 2015

Tyler Perry is this week's celebrity guest announcer.

Shaquille O'Neal

4 - Shaquille O'Neal

Air Date: October 6, 2015

Guest announcer Shaq joins Neil for an evening full of fun, games and housewives, with special guests Gloria Estefan, Zachary Levi and Blue Man Group.

Jack Black

5 - Jack Black

Air Date: October 13, 2015

Guest announcer Jack Black plus Olympic Gold medalist Apolo Ohno, and journalists Matt Lauer and Savannah Guthrie.

Reba

6 - Reba

Air Date: October 20, 2015

Guest announcer Reba plus singer OMI, and actors Jesse Tyler Ferguson and Jane Krakowski.

Kelly Ripa

7 - Kelly Ripa

Air Date: October 27, 2015

Guest announcer Kelly Ripa plus singer Ray Parker Jr. and journalist Meredith Vieira.

Kelsey Grammer

8 - Kelsey Grammer

Air Date: November 3, 2015

Guest announcer Kelsey Grammer, the Backstreet Boys perform, plus Olympic gold medalist Apolo Ohno.