Reunited by their father's death, estranged siblings with extraordinary powers uncover shocking family secrets -- and a looming threat to humanity.

Blasted back in time to 1960s Dallas, the scattered siblings build new lives for themselves — until a new doomsday threat pulls them back together.

Back at the Academy, the Umbrellas clash with a new squad of Hargreeves siblings as a mysterious force begins to wreak havoc on the city.

Six years after the reset, the powerless Hargreeves clan faces a secret society and learns that the greatest threat to the universe... may be themselves.