Euphoria follows a group of high schoolers as they explore the worlds of drugs, sexuality, and violence.

The lines between fantasy and reality begin to blur as Kat contemplates ending her relationship and Jules, craving Rue's affection, ponders hers. Rue pursues a new dangerous business venture as she sinks deep into her addiction, largely caused by her guilt-ridden new friend Eliott. Cassie struggles with her celibacy and starts to drift, while Lexi pours herself into mounting a school play. Nate is in full redemption, trying to redeem the mistakes of his father.